Ilija Nestorovski is perhaps the only bright spot of the campaign so far.
Their home record is absolutely disastrous, losing all five matches at the Stadio Barbera, scori澳门外围投注ng two goals and conceding 12.
Palermo bench: Marson, Fulignati, Vitiello, Goldaniga, Chochev, Quaison, Diamanti, Buoy, Jajalo, Morganella, Pezzella, Lo Faso
It means Giacomo Bonaventura is pushed into a more advanced role in the trident with Carlos Bacca and Suso.
Milan bench: Gabriel, Plizzari, Ely, Luiz Adriano, Lapadula, Honda, Mati Fernandez, Gomez, Poli, Zapata, Sosa, Antonelli
In turn, his old midfield spot is filled by Mario Pasalic, who finally got his debut last week after joining on loan from Chelsea in August.
This game sees an intriguing battle between the youngest goalkeepers in Serie A, as 20-year-old Josip Posavec and 17-year-old Gianluigi Donnarumma put together are still younger than Gigi Buffon.
Palermo are in familiar territory, namely the relegation zone and havi真人外围投注ng already fired one Coach (Davide Ballardini) with his replacement hanging by a thread.
It kicks off at the Stadio Barbera at 14.00 GMT,
Milan: Donnarumma; Abate, Paletta, Romagnoli, De Sciglio; Kucka, Locatelli, Pasalic; Su21点官网so, Bacca, Bonaventura
Palermo: Posavec; Cionek, Andelkovic, Rajkovic, Aleesami; Bruno Henrique, Gazzi, Hiljemark; Embalo, Nestorovski, Sallai
Gabriel Paletta returns from suspension to bolster the defence, while Mati Fernandez and Luca Antonelli are available after lengthy lay-offs.
Roberto De Zerbi has to find a way of turning this season around after one point from the last six games.
The Sicilians have lost six of their last eight meetings with Milan, home and away, with a lone 2-0 victory at San Siro in November 2014 and 2-2 draw at the Barbera in October 2012. The Rossoneri are unbeaten in this Serie A fixture since a 1-0 in March 2011.
M’Baye Niang hasn’t made the trip to Sicily due to flu symptoms, remaining behind with injured Andrea Bertolacci, Davide Calabria, Riccardo Montolivo and Leonel Vangioni.
The Rossoneri have been on fine form lately, winning six of the last eight rounds, interrupted only by a 3-0 hammering by Genoa when squad rotation went too far.
Milan aim to consolidate third place with their trip to a Palermo side in crisis, but are forced into changes upfront.
The injuries are also starting to pile up, as Andrea Rispoli, Giancarlo Gonzalez, Norbert Balogh, Accursio Bentivegna and Aleksandar Trajkovski miss out.